The existing body of literature using Western blot analysis
has been primarily defined with data from tumor, immortal, and primary cells
growing in vitro. Collectively, results obtained over decades have been
integral to the dogma that up- and down-regulation of proteins can be leveraged
as Biomarkers of normal development, homeostasis, and disease. However,
in contrast to tissues which are composed of multiple cell types, cell lines
growing in culture which theoretically consist of clonal populations. Thus,
validation or modification of western blot parameters collectively established
from decades of cell line data in tissue lysates is key for Biomarker
discovery.
IMGENEX can provide you with normal post mortem, cancerous, diseased, and
normal adjacent clinical specimens matching your requirements. Custom
collection protocols are welcomed. Specimens are available as frozen or
formalin-fixed, paraffin-embedded tissue blocks, and include clinical case and
detailed pathology reports, as well as final diagnosis and staging. Learn
more about this service by visiting our website, or downloading our Tissue
Procurement literature.
Related
Products
* Tissue Arrays
* Single Tissue Slides
* Tissue & Cell Lysates
* Extraction/ Fractionation Kits
* INSTA-Blot
Ready2use WB Membranes
Author Information
IMGENEX India Pvt
Ltd. the only biotech company in Orissa and one of its kinds in